Luca Csabai

Luca Csabai
PhD Student
 lucacsab@gmail.com
Related Projects
Multi-omics Analysis of Intestinal Organoids
Analysing Host-Microbiome Interactions
Systems-level Projects on COVID19
Introduction

I am a PhD student at Eötvös Loránd University in Budapest also working in the Korcsmaros group since my bachelor studies. I have been mainly involved in the group on the computational side with the development of group resources such as SignaLink and Autophagy Regulatory Network. During my PhD I aim to learn further bioinformatics and machine learning techniques that can be applied in biological research.

I finished my BSc in Biology and MSc in Bioinformatics at the Eötvös Loránd University with both of my theses focusing on autophagy regulation. In my PhD project I focus on investigating tissue specificity of autophagy regulation in the gut, focusing on its effect on cell-cell interactions. Combined with clinical data and machine learning techniques I aim to investigate the genetic profiles of IBD patients to potentially develop personalized therapeutic strategies.

Next to my interest in science I am also an avid baker and love to explore new places around the world.

Related publications
Hajdú B, Csabai L, Márton M, Holczer M, Korcsmáros T, Kapuy O.: Oscillation of Autophagy Induction under Cellular Stress and What Lies behind It, a Systems Biology Study. Int J Mol Sci. 2023 Apr 21;24(8):7671. doi: 10.3390/ijms24087671.
Csabai L, Bohár B, Türei D, Prabhu S, Földvári-Nagy L, Madgwick M, Fazekas D, Módos D, Ölbei M, Halka T, Poletti M, Kornilova P, Kadlecsik T, Demeter A, Szalay-Bekő M, Kapuy O, Lenti K, Vellai T, Gul L, Korcsmáros T.: AutophagyNet: high-resolution data source for the analysis of autophagy and its regulation. Autophagy. 2023 Aug 17:1-15. doi: 10.1080/15548627.2023.2247737.
Csabai L, Fazekas D, Kadlecsik T, Szalay-Bekő M, Bohár B, Madgwick M, Módos D, Ölbei M, Gul L, Sudhakar P, Kubisch J, Oyeyemi OJ, Liska O, Ari E, Hotzi B, Billes VA, Molnár E, Földvári-Nagy L, Csályi K, Demeter A, Pápai N, Koltai M, Varga M, Lenti K, Farkas IJ, Türei D, Csermely P, Vellai T, Korcsmáros T.: SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks. Nucleic Acids Res. 2022 Jan 7;50(D1):D701-D709. doi: 10.1093/nar/gkab909.
Poletti M, Treveil A, Csabai L, Gul L, Modos D, Madgwick M, Olbei M, Bohar B, Valdeolivas A, Turei D, Verstockt B, Triana S, Alexandrov T, Saez-Rodriguez J, Stanifer ML, Boulant S, Korcsmaros T.: Mapping the epithelial-immune cell interactome upon infection in the gut and the upper airways. NPJ Syst Biol Appl. 2022 May 2;8(1):15. doi: 10.1038/s41540-022-00224-x.
Bohár B, Fazekas D, Madgwick M, Csabai L, Olbei M, Korcsmaros T, Szalay-Beko M.: Sherlock: an open-source data platform to store, analyze and integrate Big Data for biology [version 1; peer review: 2 approved with reservations]. F1000Research 2021, 10:409. doi: 10.12688/f1000research.52791.1
Treveil A, Bohar B, Sudhakar P, Gul L, Csabai L, Olbei M, Poletti M, Madgwick M, Andrighetti T, Hautefort I, Modos D, Korcsmaros T.: ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways. PLoS Comput Biol. 2021 Feb 3;17(2):e1008685. doi: 10.1371/journal.pcbi.1008685. eCollection 2021 Feb.
Olbei M, Thomas JP, Hautefort I, Treveil A, Bohar B, Madgwick M, Gul L, Csabai L, Modos D, Korcsmaros T.: CytokineLink: A Cytokine Communication Map to Analyse Immune Responses-Case Studies in Inflammatory Bowel Disease and COVID-19. Cells. 2021 Aug 29;10(9):2242. doi: 10.3390/cells10092242.
Demeter A, Romero-Mulero MC, Csabai L, Ölbei M, Sudhakar P, Haerty W, Korcsmáros T.: ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins. Sci Rep. 2020 Jul 2;10(1):10940. doi: 10.1038/s41598-020-67780-2.
Csabai L, Ölbei M, Budd A, Korcsmáros T, Fazekas D.: SignaLink: Multilayered Regulatory Networks. Methods Mol Biol. 2018;1819:53-73. doi: 10.1007/978-1-4939-8618-7_3.